Serum lipoprotein accumulation in the livers of orotic acid-fed rats
نویسندگان
چکیده
منابع مشابه
Fatty Livers Induced by Orotic Acid
Rats fed a purified diet supplemented with erotic acid (1%) have gross alterations in their lipid metabolism that can be essentially nullified by further supplementation of the diet with adenine sulfate (0.25%), as described in the first paper of this series (1). Accompanying these changes are certain alterations in the metabolism of pyrimidine derivatives, which have been described in an earli...
متن کاملNascent high density lipoproteins from liver perfusates of orotic acid-fed rats.
Uniformly fatty livers from orotic acid-fed rats secreted almost no very low density lipoproteins (VLDL) but normal amounts of nascent high density lipoproteins (HDL) accumulated in perfusates. When lecithin:cholesterol acyltransferase (LCAT) was inhibited, nascent HDL were uniformly discoidal and lacked cholesteryl esters. Lipid and apoprotein compositions of nascent HDL from normal and fatty ...
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15 صفحه اولLC-MS-based metabolomic analysis of serum and livers from red ginseng-fed rats
Serum and liver metabolites in rats fed red ginseng (RG) were analyzed by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. The mass data were analyzed by partial least squares-discriminant analysis (PLS-DA) to discriminate between control and RG groups and identify metabolites contributing to this discrimination. The RG group was clearly separated from the co...
متن کاملBiochemical and Nutritional Studies on the Induction of Fatty Livers by Dietary Orotic Acid.
3Canellakis, E. S., Biochim. Biophys. Acta, 25, 217 (1957). 4Hecht, L. I., P. C. Zamecnik, M. L. Stephenson, and J. F. Scott, J. Biol. Chem., 233, 954 (1958). 6 Zachau, H. G., G. Acs, and F. Lipmann, these PROCEEDINGS, 44, 885 (1958). 6 Preiss, J., P. Berg, J. Ofengand, F. H. Bergman, and M. Dieckman, these PROCVEDINGS, 45, 319 (1959). 7Hecht, L. I., M. L. Stephenson, and P. C. Zamecnik, these ...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1971
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)39494-3